The Virgo full moon on Saturday, February 27, 2021, is linked to Saturn square Uranus. So the spiritual meaning of full moon February 2021 astrology relates to making or dealing with difficult changes.
But the February 2021 full moon makes positive change more likely and easier to implement. It is ideal for making changes that are long overdue. This is a good full moon for freeing yourself of burdens that are no longer your responsibility.
Full Moon Meaning
Sun opposite Moon (0°00′) brings your home, family, and intimate relationships into sharper focus for the following two weeks of this moon phase. Opposing forces such as work versus home, or what you need versus what you want, create inner tension and external pressures. This can lead to conflict and crises that drain your energy.
The lunar qualities of emotions and instincts reach their peak at a full moon. So use your increased emotional strength and intuition to overcome any relationship challenges. Subconscious awareness allows for an impartial and balanced look at your personal relationships. You will clearly see any relationship dynamics or negative feelings causing disharmony.
Saturn square Uranus (0°44′) creates a conflict between responsibility and independence, stability and change, duty and freedom, traditional and progressive, obedience and rebellion, routine and excitement, religion and science, conservative and liberal, sane and crazy, old and new, and the past and the future.
As a result, changes can occur that you don’t want or are challenging to cope with. Or it can be harder to make positive changes, the kind of changes you do want. Changes in government or corporation rules and laws could restrict your choices or curtail your freedom.
As an example, on the exact day of Saturn square Uranus, February 17, Facebook banned its Australian users from accessing news in their feeds. This was in response to the Australian Government’s plan to make Facebook and Google pay for news content from publishers’ pages, like newspapers and TV stations. 
At the personal level, trying to be responsible and loyal while also being free to be yourself may be a constant battle. You may have difficulty obeying rules that you feel limit your freedom, creativity, and self-expression. Disagreements about your level of commitment or inability to change could lead to a sudden relationship breakup or career changes.
This can be a very frustrating time of rising tension and difficult changes. If you rebel too much you will lose support and the stability and security you need for success. But sticking to a routine and always toeing the line will block your creativity and increase your tension to boiling point.
It is best not to force change that you want but to adapt to changing conditions. With open-mindedness, patience, flexibility, cooperation, and compromise, crises can be turned into opportunities. You can find creative breakthroughs and rid yourself of negative and limiting conditions.